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Dr.Valtrex
Wysłany: Pią 2:41, 13 Kwi 2007
Temat postu: What is valtrex?
However, no dosage adjustment is necessary at this dose of 1g because of the wide therapeutic index of aciclovir
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Common side effects include headache, nausea, vomiting, stomach pain, dizziness, cold, and sore throat
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10%), and decreased platelet counts (3% vs
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The birth defects described amongst aciclovir exposed subjects have not shown any uniqueness or consistent pattern to suggest a common cause
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Dosage adjustments should be made in patients with varying degrees of renal dysfunction
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Even with treatment it may be possible to spread genital herpes
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The usual dose for the first attack is 1 gram twice a day for 10 days
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A post-marketing acyclovir pregnancy registry has documented pregnancy outcomes in women exposed to Valtrex or any formulation of Zovirax (aciclovir, the active metabolite of valaciclovir)
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If you are taking Valtrex for shingles, you should start using it as soon as possible after your doctor has made a diagnosis
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To keep the condition from returning, the dose is 1 gram once a day
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8% for patients receiving VALTREX compared with 0
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The dosage for each type of treatment should be decided
by your doctor, but these are the general guidelines
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You don't have to eat at the same time you take Valtrex, but eating at the same time might keep you from getting an upset stomach
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It is also used to treat genital herpes in patients with normal immune systems
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People with kidney problems are more likely to get side effects or even more kidney problems from taking Valtrex
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The daily aciclovir AUC (area under plasma concentration-time curve) following Valtrex 1000 mg and 8000 mg would be approximately 2 and 9 times greater than that expected with oral aciclovir 1000 mg daily, respectively
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Please refer to the rec
ommended dosing adjustments in the Prescribing Information for VALTREX
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While taking VALTREX for cold sores, you should not exceed one day of treatment, two doses taken 12 hours apart
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Valacyclovir can also be used to control genital herpes outbreaks in all patients, including those with HIV
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Valtrex doesn't cure the infections, but it can slow down the viruses and prevent them from spreading
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Important Information About VALTREX VALTREX is for adults with healthy immune systems and is available by prescription only
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1%)
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Stopping therapy to
o soon may result in ineffective treatment
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Tell your doctor if you have kidney problems because the dosage may need to be changed
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If you wait until the cold sore develops, the medication might not work
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If you are taking Valtrex for cold sores, you should start using it at the earliest signs of infection, such as tingling, itching, or burning
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This gives your body's immune system a chance to kick in and fight off the infections itself
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Valtrex itself does not prevent the spread of genital herpes
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It is not kn
own if VALTREX reduces the risk of spreading genital herpes in same sex couples
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To avoid a potentially serious complication, tell your doctor if your immune system is not normal because of advanced HIV disease, bone marrow or kidney transplant
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Treatment with Valtrex should be started as soon as possible after the first appearance of symptoms (e
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In addition, older adults tend to suffer the pain of shingles for a longer time after healing has begun
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tingling, burning, blisters)
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To avoid spreading the infection, don't have sexual intercourse during a flare-up
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You may take Valtrex with or without food
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It is not known whether Valtrex passes into breast milk and how it may affect a nursing baby
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g
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Do not start, stop or change the dosage of any medicine before checking with them first
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The medication may not be effective if you wait longer than 72 hours after the first attack or 24 hours after a later attack
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, gentamicin, tobramycin), ampho
tericin B, cyclosporine, nonsteroidal anti-inflammatory drugs - NSAIDs (e
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When treating an outbreak, continue to take this medication until the full-prescribed amount is finished even if symptoms disappear
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Before taking this medication, tell your doctor if you have kidney disease
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Herpes infections are contagious and you can infect other people, even during treatment
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Always use a condom made of latex or polyurethane
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These events have been chosen for inclusion due to either their seriousness, frequency of reporting, causal connection to VALTREX, or a combination of these factors
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8% for placebo
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If any of these effects persist or worsen, notify your doctor or pharmacist promptly
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The medication may not work as well if you wait more than 72 hours to start it
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They're blue with white writing on them
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8%), fatigue (8% vs
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Even during treatment, you can infect other people with herpes
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Mark sure you are dealing with a reputable merchant
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VALTREX may not prevent all recurrences
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5%), and rash (8% vs
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, doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it
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Aciclovir is eliminated primarily unchanged in the urine via active tubular secretion
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If your kidneys are not functioning properly, or you are taking drugs that may damage the kidneys such as Neomycin or Streptomycin, Valtrex can make your condition worse or affect your central nervous system (brain and spinal cord)
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No data are available on the efficacy of treatment of more than 1 years duration (for suppression), started more than 72 hours (for initial) or more than 24 hours (for episodic) after onset of signs or symptoms, started after the development of clinical signs of a cold sore, or started more than 72 hours after rash onset (for herpes zoster)
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Valacyclovir is used to treat cold sores (herpes labialis) and shingles (herpes zoster)
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Nausea, vomiting, fatigue, dizziness, stomach pain, painful periods may occur
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Don't buy Valtrex from places like Asia, India or South America or the Caribbean
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ex
Patients with kidney problems or HIV infection may need a reduced dosage
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The symptoms may improve before your body's immune system has had a chance to fully fight the infection
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When using this drug to suppress/control outbreaks, take exactly as directed by your doctor
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You may need a lower dose or special monitoring during therapy with Valtrex
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The efficacy of VALTREX for reducing transmission of genital herpes has not been established in immunocompromised patients and nonheterosexual couples
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ciclospor
in, tacrolimus)
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Suppression of Genital Herpes in HIV-Infected Patients: In HIV-infected patients, frequently reported adverse events for VALTREX (500 mg twice daily; n = 194, median days on therapy = 172) and placebo (n = 99, median days on therapy = 59), respectively, included headache (13% vs
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If you are using Valtrex for genital herpes, begin taking it at the first sign of an attack
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confusion, speech problems, shaky/unsteady movement, vision changes
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It's best to see a doctor and start the drug within 48 hours of first noticing the rash
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Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e
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Even with treatment it may be possible to spread genital herpes
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You may take Valtrex with or without food
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Tell your doctor immediately if any of these rare but very serious side effects occur: change in the amount of urine, easy bruising/bleeding, unusual fever
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High doses of Valtrex have proved dangerous in people whose immune system is compromised because of HIV infection, bone marrow transplant, or kidney transplant
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Please refer to the recommended dosing adjustments in the Prescribing Information for VALTREX
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Common side effects include headache, nausea, vomiting, stomach pain, dizziness, cold, and sore throat
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The medication may not be effective if you wait longer than 72 hours after the first attack or 24 hours after a later attack
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Do not take this medication without first talking to your doctor if you are breast-feeding a baby
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Valtrex should only be used in pregnancy if the potential benefits of treatment outweigh the potential risk
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These places have poor quality control and you can not be sure what you're getting if it gets to you at all
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Alternative agents, which do not interact with other agents excreted primarily via the kidney, may be considered for the management of excess gastric acid production and urate-lowering therapy when administering high dose valaciclovir
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If any of these effects persist or worsen, notify your do
ctor or pharmacist promptly
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, fever, persistent sore throat)
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There is no cure for herpes
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The frequencies of abnormal ALT (>2 x ULN) were 1
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Effects on the central nervous system are more common in older adults, leading to such symptoms as agitation, confusion, and hallucinations
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You should drink a full glass of water with the pill
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A post-marketing acyclovir pregnancy registry has documented pregnancy outcomes in women exposed to Valtrex or any formulation of Zovirax (aciclovir, the active metabolite of valaciclovir)
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In addition, older adults tend to suffer the pain of shingles for a longer time after healing has begun
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This medication may rarely cause a blood disorder (thrombotic thrombocytopenic purpura) or a severe kidney problem (hemolytic uremic syndrome)
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Dosage is based on your medical condition and response to therapy
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Dosage adjustments should be made in patients with varying degrees of renal dysfunction
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Consider expiration dates before buying too many at once
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Probenecid (Benemid) and cimetidine (Ta
gamet, Tagamet HB) may increase the effects of Valtrex and possibly lead to dangerous side effects
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Read the Patient Information Leaflet available from your pharmacist
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Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: cimetidine, probenecid
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Consult your doctor or pharmacist if you have any questions
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Valtrex is in the FDA pregnancy category B
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10%), and decreased platelet counts (3% vs
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Tell your doctor or pharmacist if you are also using other drugs which may be harmful to your kidneys such as: aminoglycosides (e
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Following 1g Valtrex, cimetidine and probenecid increase the AUC of aciclovir by this mechanism, and reduce aciclovir renal clearance
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ciclosporin, tacrolimus)
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The usual dose for the first attack is 1 gram twice a day for 10 days
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1%)
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The efficacy of VALTREX for reducing transmission of genital herpes has not been established
in immunocompromised patients and nonheterosexual couples
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OTHER USES: This medication may be used to prevent or treat other types of viral infections (cytomegalovirus) in certain patient populations
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There's also no evidence that it will prevent transmission of the disease
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Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products
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These events have been chosen for inclusion due to either their seriousness, frequency of reporting, causal connection to VALTREX, or a combination of these factors
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Take the full Valtrex prescription, even if you fe
el better and the symptoms improve
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5%), and rash (8% vs
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When treating an outbreak, continue to take this medication until the full-prescribed amount is finished even if symptoms disappear
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Even during treatment, you can infect other people with herpes
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Suppression of Genital Herpes in HIV-Infected Patients: In HIV-infected patients, frequently reported adverse events for VALTREX (500 mg twice daily; n = 194, median days on therapy = 172) and placebo (n = 99, median days on therapy = 59), respectively, included headache (13% vs
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8% for patie
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VALTREX has not been shown to reduce transmission of sexually transmitted infections other than HSV-2
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It is also used to treat genital herpes in patients with normal immune systems
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The symptoms may improve before your body's immune system has had a chance to fully fight the infection
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Drink plenty of fluids while taking this medication
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This is also known as suppressive therapy
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When using this drug to suppress/control outbr
eaks, take exactly as directed by your doctor
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There is no cure for herpes, and even with treatment, it may be possible to spread herpes
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Aciclovir is eliminated primarily unchanged in the urine via active tubular secretion
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Do not start, stop or change the dosage of any medicine before checking with them first
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2 Pharmacokinetic Properties)
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When you have symptoms or are experiencing an outbreak, do not have sexual contact with your partner
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Increases in plasma AUCs of aciclovir and of the inactive metabol
ite of mycophenolate mofetil, an immunosuppressant agent used in transplant patients, have been shown when the drugs are coadministered; there is limited clinical experience with the use of this combination
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Valtrex comes in a caplet form that you swallow
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Don't buy Valtrex from places like Asia, India or South America or the Caribbean
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When taking VALTREX for cold sores, treatment should not exceed 1 day (2 doses taken 12 hours apart)
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Valtrex doesn't cure the infections, but it can slow down the viruses and prevent them from spreading
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Post-randomization laboratory abnormalities that were reported more frequently in valacyclovir subjects versus placebo included elevated alkaline phosphatase (4% vs
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Tell your doctor immediately if any of these rare but very serious side effects occur: seizures, loss of consciousness, signs of other infections (e
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Reduction of Transmission: In a clinical study for the reduction of transmission of genital herpes, the adverse events reported by patients receiving VALTREX 500 mg once daily (n = 743) or placebo once daily (n = 741) included headache (VALTREX 29%, placebo 26%), nasopharyngitis (VALTREX 16%, placebo 15%), and upper respiratory tract infection (VALTREX 9%, placebo 10%)
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It is not known if VALTREX reduces the risk of spreading genital herpes in same sex couples
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Your symptoms may start to improve before the infection is completely treated
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Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects
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